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Pressure BioSciences, Inc. Reports Third Quarter Financial Results

WEST BRIDGEWATER, Mass.--(BUSINESS WIRE)--Nov. 13, 2006--Pressure BioSciences, Inc. (NASDAQ: PBIO) today announced that revenue for the three months ended September 30, 2006 was $92,211 as compared to $11,742 for the three months ended September 30, 2005. This increase in revenue was driven by the sales of three PCT Sample Preparation Systems (PCT SPS) during the third quarter of 2006 (to Johns Hopkins University, the National Institutes of Health, and a state laboratory in Virginia). The Company incurred an operating loss from continuing operations of $829,835 in the third quarter of 2006, as compared to an operating loss from continuing operations of $538,902 in the same period of 2005. This increase in operating loss was the result of significant investments made in the Company's research and development and sales and marketing functions during 2006.

For the nine months ended September 30, 2006, revenue was $174,409 as compared to $21,984 for the nine months ended September 30, 2005. This increase in revenue was driven by the sales of five PCT Sample Preparation Systems during the first nine months of 2006 as compared to no PCT SPS sales during the same period in 2005. The Company incurred an operating loss from continuing operations of $2,987,098 during the first nine months of 2006, compared to an operating loss from continuing operations of $1,868,563 during the same period of 2005. The operating loss for 2006 includes $543,220 of non-cash, stock-based compensation charges incurred as per the provisions of Statement of Financial Accounting Standards Board Statement 123R "Share-Based Payment". This increase in operating loss was also the result of increased investments in all major areas of the Company's business, particularly research and development and sales and marketing. Consistent with its business strategy, the Company expects to continue to increase investments in all functional areas of its business in order to support the full commercialization of its novel and patented Pressure Cycling Technology (PCT).

As of September 30, 2006, the Company had cash and cash equivalents of approximately $5.9 million, total working capital of approximately $6.4 million, and marketable securities of approximately $2.5 million. Edward H. Myles, Vice President of Finance and CFO commented: "We are pleased to have made such significant and successful strides down the path towards full PCT commercialization, while concomitantly being able to closely manage our important financial resources."

Richard T. Schumacher, Founder, President, and CEO commented: "We continue to make significant progress in many areas of our business plan. In addition to filling key positions within our senior management team, building our R&D and marketing capabilities, and making measured progress in the development of new PCT-related products, we have also realized significant success in expanding our collaboration program with key scientific and industry leaders nationwide. We are extremely pleased that some of our collaborators have purchased the PCT Sample Preparation System following their evaluation, while others have published or presented data citing the clear benefits of PCT. We appreciate the work that our nearly 30 collaborators have done to date, and look forward to continuing to work with them as we build interest in this very important, enabling technology."

About Pressure BioSciences, Inc.

Pressure BioSciences, Inc. (PBI) is a publicly traded, early-stage company focused on the development of a novel, enabling technology called Pressure Cycling Technology (PCT). PCT uses cycles of hydrostatic pressure between ambient and ultra-high levels (up to 35,000 psi and greater) to control bio-molecular interactions. PBI currently holds 13 US and 5 foreign patents covering multiple applications of PCT in the life sciences field, including such areas as genomic and proteomic sample preparation, pathogen inactivation, the control of enzymes, immunodiagnostics, and protein purification.

Forward Looking Statements

Statements contained in this press release regarding the Company's intentions, hopes, beliefs, expectations, or predictions of the future are "forward-looking'' statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements are based upon the Company's current expectations, forecasts, and assumptions that are subject to risks, uncertainties, and other factors that could cause actual outcomes and results to differ materially from those indicated by these forward-looking statements. These risks, uncertainties, and other factors include, but are not limited to: possible difficulties or delays in the implementation of the Company's strategies that may adversely affect the Company's continued commercialization of its PCT Sample Preparation System; the Company's financial results for the three and nine months ended September 30, 2006 may not necessarily be indicative of future results as future revenues may not meet expectations due to changes in customers needs and technological innovations, and expenses may be higher than anticipated due to unforeseen cost increases; the Company's collaboration programs may not continue to be successful and may not result in the sale of additional PCT Systems to collaborators or others; and the Company may be unable to develop any new PCT-related products that achieve commercial acceptance. Additional risks and uncertainties that could cause actual results to differ materially from those indicated by these forward-looking statements are discussed under the heading "Risk Factors" in the Company's Quarterly Report on Form 10-QSB for the quarter ended September 30, 2006, in the Company's Annual Report on Form 10-KSB, as amended, for the year ended December 31, 2005, and other reports filed by the Company from time to time with the SEC. The Company undertakes no obligation to update any of the information included in this release, except as otherwise required by law.

Visit us at our website http://www.pressurebiosciences.com

Consolidated Statements of Operations (Unaudited)

                      For the Three Months   For the Nine Months Ended
                              Ended
                          September 30,            September 30,
                     ----------------------- -------------------------
                        2006        2005        2006         2005
                     ----------- ----------- ------------ ------------
                                 (restated)                (restated)
REVENUE:
 PCT Products,
  services, other    $   92,211  $   11,742  $   174,409  $    21,984
                     ----------- ----------- ------------ ------------
    Total revenue        92,211      11,742      174,409       21,984
                     ----------- ----------- ------------ ------------

COSTS AND EXPENSES:
 Cost of PCT
  products &
  services               90,037      33,966      188,688       61,653
 Research and
  development           324,525     156,529      984,844      374,147
 Selling and
  marketing             127,419      39,954      322,803       93,590
 General and
  administrative        380,065     320,195    1,665,172    1,361,157
                     ----------- ----------- ------------ ------------
    Total operating
     costs and
     expenses           922,046     550,644    3,161,507    1,890,547
                     ----------- ----------- ------------ ------------

    Operating loss
     from continuing
     operations        (829,835)   (538,902)  (2,987,098)  (1,868,563)

OTHER INCOME
 (EXPENSE):
 Realized gain on
  securities held
  for sale                    -   2,838,491      517,938    2,838,491
 Other operating,
  net                         -    (140,648)           -     (528,285)
 Interest income         88,190      62,699      305,982      187,559
                     ----------- ----------- ------------ ------------
    Total other
     income              88,190   2,760,542      823,920    2,497,765

    (Loss) income
     from continuing
     operations
     before income
     taxes             (741,645)  2,221,640   (2,163,178)     629,202
    Income tax
     benefit
     (provision)
     from continuing
     operations         111,106    (912,671)     408,344     (457,535)
                     ----------- ----------- ------------ ------------

    (Loss) income
     from continuing
     operations        (630,539)  1,308,969   (1,754,834)     171,667

Discontinued
 operations:
 (Loss) income from
  discontinued
  operations (net of
  income tax benefit
  of $1,720 and
  provision of $913
  for the three and
  nine months ended
  in 2005)                    -      (3,340)           -        1,995

 Gain on sale of net
  assets related to
  discontinued
  operations
  (includes effect
  of income taxes of
  $701,699 in 2005)           -     701,699            -      701,699

                     ----------- ----------- ------------ ------------
    Net income from
     discontinued
     operations               -     698,359            -      703,694
                     =========== =========== ============ ============

    Net (loss)
     income          $ (630,539) $2,007,328  $(1,754,834) $   875,361
                     =========== =========== ============ ============


 (Loss) income per
  share from
  continuing
  operations - basic $    (0.26) $     0.54  $     (0.72) $      0.05
 Income per share
  from discontined
  operations - basic $        -  $     0.29  $         -  $      0.23
                     ----------- ----------- ------------ ------------
 Net (loss) income
  per share, basic   $    (0.26) $     0.83  $     (0.72) $      0.28
                     =========== =========== ============ ============

 (Loss) income per
  share from
  continuing
  operations -
  diluted            $    (0.26) $     0.52  $     (0.72) $      0.05
 Income per share
  from discontined
  operations -
  diluted            $        -  $     0.27  $         -  $      0.22
                     ----------- ----------- ------------ ------------
 Net (loss) income
  per share, diluted $    (0.26) $     0.79  $     (0.72) $      0.27
                     =========== =========== ============ ============

    Weighted average
     number of
     shares used to
     calculate net
     (loss) income
     per share -
     basic            2,422,675   2,424,189    2,424,351    3,157,495

    Weighted average
     number of
     shares used to
     calculate net
     (loss) income
     per share -
     diluted          2,422,675   2,537,987    2,424,351    3,202,101
Condensed Consolidated Balance Sheet Data

                                              September   December 31,
                                                  30,
                                                2006         2005
                                             ------------ ------------
                                             (unaudited)   (restated)

ASSETS
Cash and cash equivalents                    $ 5,850,427  $ 6,416,772
Escrow deposit related to sale of assets to
 SeraCare                                              -    1,117,305
Income tax receivable                            781,457      531,122
Prepaid expenses, deposits, and other
 current assets                                  410,933      476,436
                                             ------------ ------------
   Total current assets                        7,042,817    8,541,635
                                             ------------ ------------

PROPERTY AND EQUIPMENT, NET                      200,146      282,780

  Intangible assets, net                         389,080      425,554
  Assets transferred under contractual
   arrangements                                1,420,996    1,420,996
  Investments in marketable securities         2,549,113    3,962,810
                                             ------------ ------------
          Total other assets                   4,359,189    5,809,360
                                             ------------ ------------

                                             ------------ ------------
  TOTAL ASSETS                               $11,602,152  $14,633,775
                                             ============ ============

LIABILITIES
Current liabilities                              689,393      800,899
Long term liabilities                          1,926,380    2,468,275

                                             ------------ ------------
  TOTAL LIABILITIES                            2,615,773    3,269,174
                                             ------------ ------------

STOCKHOLDERS' EQUITY
Paid-in capital                                6,290,745    6,051,262
Loan receivable from Director / CEO           (1,000,000)  (1,000,000)
Accumulated other comprehensive income         1,675,092    2,537,963
Retained earnings                              2,020,542    3,775,376

                                             ------------ ------------
  TOTAL STOCKHOLDERS' EQUITY                   8,986,379   11,364,601
                                             ------------ ------------

                                             ------------ ------------
  TOTAL LIABILITIES & STOCKHOLDERS' EQUITY   $11,602,152  $14,633,775
                                             ============ ============

CONTACT: Pressure BioSciences, Inc.
Investor Contacts:
Richard T. Schumacher, 508-580-1818
President & CEO
or
Edward H. Myles, 508-580-1818
Vice President of Finance & CFO

SOURCE: Pressure BioSciences, Inc.

Contact Us
14 Norfolk Avenue
South Easton, MA 02375
(T) 508-230-1828
(F) 508-230-1829
info@pressurebiosciences.com