Identification of Protein Abundance Changes in Hepatocellular Carcinoma Tissues using PCT-SWATH.

Identification of Protein Abundance Changes in Hepatocellular Carcinoma Tissues using PCT-SWATH.

PURPOSE:

To rapidly identify protein abundance changes in biopsy-level fresh-frozen hepatocellular carcinoma (HCC).

CONCLUSIONS AND CLINICAL RELEVANCE:

We demonstrated the practicality of rapid proteomic analysis of biopsy-level fresh-frozen HCC tissue samples with PCT-SWATH and identified promising tumor marker candidates including MCM7.