There are over 100 scientific papers published on the advantages of the PCT platform, many by key opinion leaders worldwide. Such advantages include: (a) extraction and recovery of more membrane proteins, (b) enhanced protein digestion, (c) differential lysis in a mixed sample base, (d) pathogen inactivation, (e) increased DNA detection and (f) exquisite sample preparation process control.

High Pressure Mediated Sample Preparation for Capillary Electrophoresis Analysis of N-Linked Glycans

A. Guttman1,2, Z. Szaba1, and Barry L. Karger1 1Barnett Institute, Northeastern University, Boston, MA 02115 2HLBS, University of Debrecen, Hungary 49th EHPRG, Aug 28-Sept 2, 2011 Budapest, Hungary

A Separation-Free Quantitative MS-Based Profiling Approach Using 2-AA Isotopically Labeled Substrates for High-Throughput Glycan Screening

Justin M. Prien1, Lorna Maheu1, Brad Prater1, and Steve Cockrill1 1 Analytical Science, Amgen, Longmont, Colorado 80503

The Signature Exosome Map for Bone Marrow Stromal Cells: Development of an Optimal Sample Preparation Approach

Qin (Stefanie) Liang1, Yamei Gao2, and Michail A. Alterman1 1 Tumor Vaccines and Biotechnology Branch, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research,US Food and Drug Administration,Silver Spring, MD, United States. 2 Laboratory of Pediatric and Respiratory Viral Diseases, Division of Viral Products, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, United States

Use of Laser Capture Microdissection with Pressure Cycle Sample Preparation to Analyze the Proteome of Retinal Sub-Structures

Sascha Dammeier1, Eloed Koertvely2, Michelle Dierstein2, Franziska Klose3, Katja Schenke-Layland4, Marius Ueffing1 1Institute for Ophthalmic Research, University of Tuebingen, Tuebingen, Germany 2Institute for Ophthalmic Research, Eberhard-Karls-UniversityTuebingen, Tuebingen, Germany 3University Hospital Tuebingen, Medical Proteome Center, Tuebingen, Germany 4University Of Tuebingen, University Women's Hospital, Tuebingen, Germany (Abstract Only)

Effective Semi-Automated Extraction of Intact Mitochondria from Solid Tissues Using Gentle Mechanical Homogenization and Pressure Cycling Technology

Vera S. Gross1, Greta Carlson1, Emily Freeman2, Alexander R. Ivanov2, Heather Greenberg3, Sergei Baranov3, Irina Stavrovskaya3, Bruce Kristal3, Alexander Lazarev1 1Pressure BioSciences, Inc., South Easton, MA 2HSPH Proteomics Resource, Harvard School of Public Health, Boston, MA 3Brigham and Women's Hospital; Harvard University, Boston, MA