Proteomics

Strategies to enable large-scale proteomics for reproducible research

Rebecca C. Poulos,^#1 Peter G. Hains,^#1 Rohan Shah,^#1 Natasha Lucas,¹ Dylan Xavier,¹ Srikanth S. Manda,¹ Asim Anees,¹ Jennifer M. S. Koh,¹ Sadia Mahboob,¹ Max Wittman,¹ Steven G. Williams,¹ Erin K. Sykes,¹ Michael Hecker,¹ Michael Dausmann,¹ Merridee A. Wouters,¹ Keith Ashman,² Jean Yang,³ Peter J. Wild,^4,5 Anna deFazio,^6,7,8 Rosemary L. Balleine,¹ Brett Tully,¹ Ruedi Aebersold,^9,10 Terence P. Speed,^11,12 Yansheng Liu,^13,14 Roger R. Reddel,¹ Phillip J. Robinson,¹ and Qing Zhong¹

Molecular Epitope Determination of Aptamer Complexes of the Multi‐domain Protein C‐Met by Proteolytic Affinity‐ Mass Spectrometry

Michael Przybylski; Loredana Lupu; Pascal Wiegand; Nico Hüttmann; Stephan Rawer; Wolfgang Kleinekofort; Irina Shugorevai; Anna S. Kichkailo; Felix N. Tomilin; Alexander Lazarev; Maxim V. Berezovski

Epitope Identification and Affinity Determination of an Inhibiting Human Antibody to Interleukin IL8 (CXCL8) by SPR- Biosensor–Mass Spectrometry Combination

Pascal Wiegand; Loredana Lupu; Nico Hüttmann; Julia Wack; Stephan Rawer; Michael Przybylski; Katja Schmitz

Steinbeis Centre for Biopolymer Analysis & Biomedical Mass Spectrometry, Marktstrasse 29, 65428 Rüsselsheim am Main, Germany

Techn. Universität Darmstadt, Institute of Organic Chemistry and Biochemistry, Alarich-Weiss-Strasse 8, 64287 Darmstadt, Germany

ACE over expression in myeloid cells increases oxidative metabolism and cellular ATP

Duo-Yao Cao¹, Weston R. Spivia², Luciana C. Veiras¹, Zakir Khan^1,3, Zhenzi Peng¹, Anthony E. Jones⁴, Ellen A. Bernstein¹, Suguru Saito¹, Derick Okwan-Duodu^1,3, Sarah J. Parker^2,5, Jorge F. Giani^1,3, Ajit S. Divakarun⁴, Jennifer E. Van Eyk², Kenneth E. Bernstein^1,3

¹Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048

²The Smidt Heart Institute and Advanced Clinical Biosystems Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048.

³Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048

⁴Department of Molecular and Medical Pharmacology; UCLA David Geffen School of Medicine; Los Angeles CA 90095.

⁵Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048.

Pressure Cycling Technology‐Assisted Mass Spectrometric Quantification of Gingival Tissue Reveals Proteome Dynamics During the Initiation and Progression of Inflammatory Periodontal Disease

Xiaofei Li; Tetsuhiro Kajikawa; Abe Toshiharu; Nathalie Selevsek; Jonas Grossmann; George Hajishengallis; Nagihan Bostanci